HRE 664, a new parenteral penem. I. Antibacterial activity in vitro.
نویسندگان
چکیده
The new penem antibiotic HRE 664 displays potent antibacterial activity in vitro against a broad spectrum of clinically relevant bacterial strains including Gram-negative and Gram-positive aerobes and anaerobes. With an MIC 90% of 0.43 micrograms/ml, it is also active against methicillin-resistant staphylococci. HRE 664 is extremely stable against beta-lactamases, it binds preferentially to the penicillin-binding proteins 2, 3, 5 and 6 of Escherichia coli.
منابع مشابه
Antibacterial activity of HRE 664, a new parenteral penem.
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ورودعنوان ژورنال:
- The Journal of antibiotics
دوره 40 5 شماره
صفحات -
تاریخ انتشار 1987